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Filtered:
UNIPROT:P51692 (8 hits)
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Pathway evidence source
Curated
inferred
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Index
ErbB signaling pathway
Growth hormone receptor signaling
Jak-STAT signaling pathway
Motif
Protein
Start
End
Switch Type
Switch Subtype
Switch description
Information
Evidence
ErbB signaling pathway
(
KEGG - hsa04012
)
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Curated
Growth hormone receptor signaling
(
Reactome - 982772
)
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Curated
Jak-STAT signaling pathway
(
KEGG - hsa04630
)
LIG_SH2_III
GHR_HUMAN
428
444
Binary
Physicochemical compatibility
Phosphorylation of Y436 in the SH2-binding motif of
Growth hormone receptor (GHR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
IL2RB_HUMAN
528
544
Binary
Physicochemical compatibility
Phosphorylation of Y536 in the SH2-binding motif of
Interleukin-2 receptor subunit beta (IL2RB)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
EPOR_HUMAN
360
376
Binary
Physicochemical compatibility
Phosphorylation of Y368 in the SH2-binding motif of
Erythropoietin receptor (EPOR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
EPOR_HUMAN
418
434
Binary
Physicochemical compatibility
Phosphorylation of Y426 in the SH2-binding motif of
Erythropoietin receptor (EPOR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
EPOR_HUMAN
496
508
Binary
Physicochemical compatibility
Phosphorylation of Y504 in the SH2-binding motif of
Erythropoietin receptor (EPOR)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Inferred
LIG_SH2_III
STA5A_HUMAN
686
702
Binary
Physicochemical compatibility
Phosphorylation of Y694 in the SH2-binding motif of
Signal transducer and activator of transcription 5A (STAT5A)
induces binding to the
Signal transducer and activator of transcription 5B (STAT5B)
protein.
details
Curated
