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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: ELM:DEG_SCF_FBW7_2 (2 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
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Large T antigen (Simian)Neurogenic locus notch homolog protein 1


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Large T antigen - -  Simian virus 40
DEG_SCF_FBW7_2699705BinaryPhysicochemical compatibilityPhosphorylation of T701 in the degron of Large T antigen induces binding to the F-box/WD repeat-containing protein 7 (FBXW7) protein, which recruits it to the SCF ubiquitin ligase complex where it is marked for degradation.
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Neurogenic locus notch homolog protein 1 - NOTCH1 -  Homo sapiens
DEG_SCF_FBW7_225082515BinaryPhysicochemical compatibilityPhosphorylation of T2511 in the degron of Neurogenic locus notch homolog protein 1 (NOTCH1) induces binding to the F-box/WD repeat-containing protein 7 (FBXW7) protein, which recruits it to the SCF ubiquitin ligase complex where it is marked for degradation.
details
           
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