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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:Q05397 (4 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
Focal adhesion kinase 1Paxillin


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Focal adhesion kinase 1 - PTK2 -  Homo sapiens
DOC_WW_Pin1_4907912BinaryPhysicochemical compatibilityPhosphorylation of S910 in the Pin1-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein.
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LIG_SH2_IA389405BinaryPhysicochemical compatibilityPhosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Cytoplasmic protein NCK2 (NCK2) protein.
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LIG_SH2_SRC397400BinaryPhysicochemical compatibilityPhosphorylation of Y397 in the SH2-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to Neuronal proto-oncogene tyrosine-protein kinase Src (Src).
details

Paxillin - PXN -  Homo sapiens
LIG_FAT_LD_1412BinaryPre‑translationalAlternative splicing removes the FAK-binding LD motif of Paxillin (PXN), abrogating binding to Focal adhesion kinase 1 (PTK2).
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