switches.ELM

Predicted switches in the ELMs Resource

General :Overview Visualisation Statistics

Subsets

Avidity : Avidity-sensing

Specificity : Altered binding specificity Competition Domain hiding Motif hiding

Cumulative : Rheostatic

Pre-assembly : Composite binding site formation

Binary : Allostery Physicochemical compatibility Pre-translational Defined PTM-induced

Binary - Pre-translational

Pre-translational mechanisms such as alternative splicing, alternative promoter-usage and/or RNA editing result in inclusion or removal of exons that contain an entire or partial motif.

Accession	Protein	Gene	Motif	Start	Stop	Splicing details	Vis
Q13291	Signaling lymphocytic activation molecule	SLAMF1	MOD_TYR_ITSM	323	330	Missing in isoform 2	view
P40225	Thrombopoietin	THPO	MOD_N-GLC_1	196	201	Missing in isoform 3	view
Q62406	Interleukin-1 receptor-associated kinase 1	Irak1	LIG_TRAF6	700	708	Missing in isoform 2	view
Q9QUH6	Ras GTPase-activating protein SynGAP	Syngap1	LIG_PDZ_Class_1	1303	1308	Missing in isoform 5, 2, 4	view
Q8C351	Layilin	Layn	LIG_PTB_Apo_2	374	381	Missing in isoform 2	view
Q8WTV1	THAP domain-containing protein 3	THAP3	LIG_HCF-1_HBM_1	177	180	Missing in isoform 3	view
Q7Z6J0	E3 ubiquitin-protein ligase SH3RF1	SH3RF1	LIG_SIAH_1	600	608	Missing in isoform 2	view
Q5JSH3	WD repeat-containing protein 44	WDR44	TRG_ER_FFAT_1	4	15	Missing in isoform 3	view
Q9BZ71	Membrane-associated phosphatidylinositol transfer protein 3	PITPNM3	TRG_ER_FFAT_1	29	40	Missing in isoform 2	view
Q9C0H9	SRC kinase signaling inhibitor 1	SRCIN1	LIG_SxIP_EBH_1	1032	1046	Missing in isoform 3, 2	view
O00499	Myc box-dependent-interacting protein 1	BIN1	LIG_AP2alpha_1	362	366	Missing in isoform BIN1-10-13, BIN1-13, II3, BIN1, IIC1, IIC2, IID	view
O00499	Myc box-dependent-interacting protein 1	BIN1	LIG_Clathr_ClatBox_1	390	394	Missing in isoform BIN1-10-13, BIN1-13, II3, BIN1, IIC1, IIC2, II2, BIN1, IIB	view
O00499	Myc box-dependent-interacting protein 1	BIN1	LIG_Clathr_ClatBox_2	415	420	Missing in isoform BIN1-10-13, BIN1-13, II3, BIN1, IIC1, IIC2, II2, BIN1, IIB	view
Q03347	Runt-related transcription factor 1	Runx1	LIG_WRPW_1	448	451	Missing in isoform 3, 5	view
P03519	Matrix protein	M	LIG_WW_1	24	27	Missing in isoform M3, M2	view
P40421	Serine/threonine-protein phosphatase rdgC	rdgC	LIG_IQ	6	25	Missing in isoform A	view
P32004	Neural cell adhesion molecule L1	L1CAM	TRG_ENDOCYTIC_2	1176	1179	Missing in isoform 2	view
P21860	Receptor tyrosine-protein kinase erbB-3	ERBB3	LIG_PTB_Phospho_1	1322	1328	Missing in isoform 2, 3	view
P05771	Protein kinase C beta type	PRKCB	LIG_AGCK_PIF_1	657	662	Missing in isoform Beta-II	view
P10276	Retinoic acid receptor alpha	RARA	LIG_WW_Pin1_4	74	79	Missing in isoform Alpha-1-deltaBC	view
Q9BX63	Fanconi anemia group J protein	BRIP1	LIG_BRCT_BRCA1_1	989	993	Missing in isoform 2	view
Q9BX63	Fanconi anemia group J protein	BRIP1	LIG_BRCT_BRCA1_2	989	995	Missing in isoform 2, 2	view
P54198	Protein HIRA	HIRA	LIG_CYCLIN_1	629	633	Missing in isoform Short	view
Q86XX4	Extracellular matrix protein FRAS1	FRAS1	LIG_PDZ_Class_1	4002	4007	Missing in isoform 4, 6, 5	view
O88829	Lactosylceramide alpha-2,3-sialyltransferase	St3gal5	TRG_ER_diArg_1	11	13	Missing in isoform 2	view
O75122	CLIP-associating protein 2	CLASP2	LIG_SxIP_EBH_1	492	502	Missing in isoform 2	view
O75122	CLIP-associating protein 2	CLASP2	LIG_SxIP_EBH_1	515	525	Missing in isoform 2	view
Q9Y5R5	Doublesex- and mab-3-related transcription factor 2	DMRT2	LIG_EH1_1	542	550	Missing in isoform 2	view
Q14980	Nuclear mitotic apparatus protein 1	NUMA1	LIG_TNKBM_1	1742	1749	Missing in isoform Numa-m, Numa-s	view
Q86Z02	Homeodomain-interacting protein kinase 1	HIPK1	LIG_KEPE_2	24	32	Missing in isoform 4, 3	view
O43432	Eukaryotic translation initiation factor 4 gamma 3	EIF4G3	LIG_eIF4E_1	624	630	Missing in isoform 2	view
Q9Z0G8	WAS/WASL-interacting protein family member 3	Wipf3	LIG_EVH1_3	425	437	Missing in isoform 2	view
G5EGD2	Hypoxia-inducible factor 1	hif-1	LIG_ODPH_VHL_1	619	631	Missing in isoform d	view
Q9NY15	Stabilin-1	STAB1	LIG_PTB_Apo_2	2536	2543	Missing in isoform 2	view
Q99K48	Non-POU domain-containing octamer-binding protein	Nono	LIG_WW_Pin1_4	409	414	Missing in isoform 2	view
Q99K48	Non-POU domain-containing octamer-binding protein	Nono	LIG_WW_Pin1_4	427	432	Missing in isoform 2	view
Q99K48	Non-POU domain-containing octamer-binding protein	Nono	LIG_WW_Pin1_4	449	454	Missing in isoform 2	view
P27986	Phosphatidylinositol 3-kinase regulatory subunit alpha	PIK3R1	LIG_SH3_1	88	94	Missing in isoform 3, 2	view
P27986	Phosphatidylinositol 3-kinase regulatory subunit alpha	PIK3R1	LIG_SH3_2	305	310	Missing in isoform 3	view
P78314	SH3 domain-binding protein 2	SH3BP2	LIG_TNKBM_1	414	421	Missing in isoform Short	view
P13285	Latent membrane protein 2	LMP2	LIG_WW_1	57	60	Missing in isoform LMP2B	view
P13285	Latent membrane protein 2	LMP2	LIG_WW_1	98	101	Missing in isoform LMP2B	view
P13497	Bone morphogenetic protein 1	BMP1	MOD_N-GLC_1	331	336	Missing in isoform BMP1-4	view
P13497	Bone morphogenetic protein 1	BMP1	MOD_N-GLC_1	362	367	Missing in isoform BMP1-4	view
P13497	Bone morphogenetic protein 1	BMP1	MOD_N-GLC_1	598	603	Missing in isoform BMP1-4, BMP1-5	view
P16471	Prolactin receptor	PRLR	LIG_SH2_STAT5	342	345	Missing in isoform 3, 7, 6, 8, 5, 4	view
P16471	Prolactin receptor	PRLR	MOD_N-GLC_1	58	63	Missing in isoform 8, 2	view
P16471	Prolactin receptor	PRLR	MOD_N-GLC_1	103	108	Missing in isoform 2	view
P16471	Prolactin receptor	PRLR	MOD_N-GLC_1	232	237	Missing in isoform 7, 3	view
P16471	Prolactin receptor	PRLR	LIG_SCF-TrCP1_1	348	353	Missing in isoform 3, 7, 6, 8, 5, 4, 5	view
P49639	Homeobox protein Hox-A1	HOXA1	LIG_HOMEOBOX	205	208	Missing in isoform 1	view
P13569	Cystic fibrosis transmembrane conductance regulator	CFTR	LIG_PDZ_Class_1	1475	1480	Missing in isoform 3	view
Q9H3D4	Tumor protein 63	TP63	LIG_MDM2	55	62	Missing in isoform 2, 4, 6, 8, 10, 12	view
Q05397	Focal adhesion kinase 1	PTK2	MOD_ProDKin_1	907	913	Missing in isoform 4, 3	view
Q05397	Focal adhesion kinase 1	PTK2	LIG_WW_Pin1_4	907	912	Missing in isoform 4, 3	view
Q05397	Focal adhesion kinase 1	PTK2	LIG_SH2_SRC	397	400	Missing in isoform 6	view
Q05397	Focal adhesion kinase 1	PTK2	LIG_SH3_2	712	717	Missing in isoform 4, 3	view
Q9NQ25	SLAM family member 7	SLAMF7	MOD_TYR_ITSM	280	287	Missing in isoform 3	view
Q07310	Neurexin-3-alpha	Nrxn3	LIG_PDZ_Class_2	1573	1578	Missing in isoform 11, 12, 13, 14, 15, 16, 9, 10	view
Q9Y6W5	Wiskott-Aldrich syndrome protein family member 2	WASF2	LIG_Actin_WH2_1	437	453	Missing in isoform 2	view
P55212	Caspase-6	CASP6	CLV_C14_Caspase3-7	20	24	Missing in isoform Beta	view
O00203	AP-3 complex subunit beta-1	AP3B1	LIG_Clathr_ClatBox_1	818	822	Missing in isoform 2	view
P50539	Max-interacting protein 1	MXI1	LIG_Sin3_1	9	19	Missing in isoform 2, 4, 3	view
P00750	Tissue-type plasminogen activator	PLAT	MOD_OFUCOSY	91	97	Missing in isoform 4	view
O89019	Inversin	Invs	LIG_IQ	556	575	Missing in isoform 5	view
O89019	Inversin	Invs	LIG_IQ	915	934	Missing in isoform 5, 6, 7	view
Q00987	E3 ubiquitin-protein ligase Mdm2	MDM2	MOD_PIKK_1	392	398	Missing in isoform Mdm2-E	view
Q00987	E3 ubiquitin-protein ligase Mdm2	MDM2	LIG_USP7_1	147	151	Missing in isoform Mdm2-B, Mdm2-A, Mdm2-A1, Mdm2-D, Mdm2-C, Mdm2-E, Mdm2-G	view
Q00987	E3 ubiquitin-protein ligase Mdm2	MDM2	LIG_USP7_1	226	230	Missing in isoform Mdm2-B, Mdm2-D, Mdm2-E	view
P05106	Integrin beta-3	ITGB3	LIG_PTB_Phospho_1	767	773	Missing in isoform Beta-3B, Beta-3C	view
P05106	Integrin beta-3	ITGB3	LIG_PTB_Phospho_1	779	785	Missing in isoform Beta-3B, Beta-3C	view
P05106	Integrin beta-3	ITGB3	LIG_PTB_Apo_2	767	774	Missing in isoform Beta-3B, Beta-3C	view
P05106	Integrin beta-3	ITGB3	LIG_PTB_Apo_2	779	786	Missing in isoform Beta-3B, Beta-3C	view
Q8N4B1	Sesquipedalian-1	FAM109A	LIG_OCRL_FandH_1	223	235	Missing in isoform 3	view
Q58A45	PAB-dependent poly(A)-specific ribonuclease subunit 3	PAN3	LIG_PAM2_1	284	296	Missing in isoform 2, 3	view
P55211	Caspase-9	CASP9	LIG_BIR_III_2	315	319	Missing in isoform 3	view
P55211	Caspase-9	CASP9	CLV_C14_Caspase3-7	327	331	Missing in isoform 3	view
Q9P0K1	Disintegrin and metalloproteinase domain-containing protein 22	ADAM22	LIG_14-3-3_3	854	859	Missing in isoform 2	view
O95081	Arf-GAP domain and FG repeat-containing protein 2	AGFG2	LIG_EH_1	365	369	Missing in isoform 2	view
O95081	Arf-GAP domain and FG repeat-containing protein 2	AGFG2	LIG_EH_1	380	384	Missing in isoform 2	view
O95081	Arf-GAP domain and FG repeat-containing protein 2	AGFG2	LIG_EH_1	458	462	Missing in isoform 2	view
O95081	Arf-GAP domain and FG repeat-containing protein 2	AGFG2	LIG_EH_1	477	481	Missing in isoform 2	view
Q15648	Mediator of RNA polymerase II transcription subunit 1	MED1	LIG_NRBOX	603	609	Missing in isoform 2	view
Q15648	Mediator of RNA polymerase II transcription subunit 1	MED1	LIG_NRBOX	644	650	Missing in isoform 2	view
P48023	Tumor necrosis factor ligand superfamily member 6	FASLG	MOD_N-GLC_1	183	188	Missing in isoform 2	view
P48023	Tumor necrosis factor ligand superfamily member 6	FASLG	MOD_N-GLC_1	249	254	Missing in isoform 2	view
P48023	Tumor necrosis factor ligand superfamily member 6	FASLG	MOD_N-GLC_1	259	264	Missing in isoform 2	view
Q09428	ATP-binding cassette sub-family C member 8	ABCC8	TRG_ER_diArg_1	648	651	Missing in isoform 3	view
Q96HZ4	Transcription cofactor HES-6	HES6	LIG_WRPW_1	221	224	Missing in isoform 2	view
Q13422	DNA-binding protein Ikaros	IKZF1	LIG_CtBP_PxDLS_1	34	38	Missing in isoform Ik4	view
P23385	Metabotropic glutamate receptor 1	Grm1	LIG_EVH1_2	1152	1156	Missing in isoform 1C, 1B	view
O60641	Clathrin coat assembly protein AP180	SNAP91	LIG_AP2alpha_1	440	444	Missing in isoform 2, 3	view
O60641	Clathrin coat assembly protein AP180	SNAP91	LIG_AP2alpha_1	564	568	Missing in isoform 2, 3	view
O60641	Clathrin coat assembly protein AP180	SNAP91	LIG_AP2alpha_1	642	646	Missing in isoform 2, 3	view
Q16821	Protein phosphatase 1 regulatory subunit 3A	PPP1R3A	LIG_PP1	61	67	Missing in isoform 2	view
Q9QY17	Protein kinase C and casein kinase substrate in neurons 2 protein	Pacsin2	LIG_EH_1	363	367	Missing in isoform 2, 4	view
P08581	Hepatocyte growth factor receptor	MET	LIG_SH2_SRC	1349	1352	Missing in isoform 3	view
P08581	Hepatocyte growth factor receptor	MET	LIG_SH2_SRC	1356	1359	Missing in isoform 3	view
P08581	Hepatocyte growth factor receptor	MET	LIG_SH2_GRB2	1356	1359	Missing in isoform 3	view
Q61183	Poly(A) polymerase alpha	Papola	MOD_ProDKin_1	534	540	Missing in isoform 2	view
Q8WWK9	Cytoskeleton-associated protein 2	CKAP2	LIG_APCC_KENbox_2	80	84	Missing in isoform 2	view
Q13255	Metabotropic glutamate receptor 1	GRM1	LIG_EVH1_2	1147	1151	Missing in isoform Beta	view
Q8CFN5	Myocyte-specific enhancer factor 2C	Mef2c	LIG_WW_Pin1_4	95	100	Missing in isoform 4, 5	view
Q8CFN5	Myocyte-specific enhancer factor 2C	Mef2c	LIG_WW_Pin1_4	107	112	Missing in isoform 4, 5	view
P40238	Thrombopoietin receptor	MPL	LIG_SH2_STAT3	631	634	Missing in isoform 2	view
Q9BSI4	TERF1-interacting nuclear factor 2	TINF2	LIG_TRFH_1	258	262	Missing in isoform 3	view
Q13936	Voltage-dependent L-type calcium channel subunit alpha-1C	CACNA1C	LIG_IQ	1666	1685	Missing in isoform 9, 26	view
P05067	Amyloid beta A4 protein	APP	LIG_PTB_Apo_2	756	763	Missing in isoform APP305	view
P05067	Amyloid beta A4 protein	APP	LIG_SH2_GRB2	757	760	Missing in isoform APP305	view
P05067	Amyloid beta A4 protein	APP	LIG_WW_Pin1_4	740	745	Missing in isoform APP305	view
Q06609	DNA repair protein RAD51 homolog 1	RAD51	LIG_SH3_1	315	321	Missing in isoform 3	view
P48356	Leptin receptor	Lepr	LIG_SH2_STAT3	1138	1141	Missing in isoform E, C, A, D	view
P10912	Growth hormone receptor	GHR	LIG_SH2_STAT5	627	630	Missing in isoform 3, 2	view
P10912	Growth hormone receptor	GHR	LIG_SH2_STAT5	566	569	Missing in isoform 3, 2	view
P10912	Growth hormone receptor	GHR	LIG_SH2_STAT5	534	537	Missing in isoform 3, 2	view
Q9CW46	Ribonucleoprotein PTB-binding 1	Raver1	LIG_RRM_PRI_1	360	367	Missing in isoform 2	view
Q9CW46	Ribonucleoprotein PTB-binding 1	Raver1	LIG_RRM_PRI_1	400	407	Missing in isoform 2	view
Q9CW46	Ribonucleoprotein PTB-binding 1	Raver1	LIG_RRM_PRI_1	499	506	Missing in isoform 2	view
Q9XWD6	Cell death abnormality protein 1	ced-1	LIG_PTB_Apo_2	959	966	Missing in isoform d	view
O00571	ATP-dependent RNA helicase DDX3X	DDX3X	LIG_eIF4E_2	38	44	Missing in isoform 2	view
Q8VIM5	Myocardin	Myocd	LIG_Actin_RPEL_3	20	39	Missing in isoform 2, 4, 5	view
Q8VIM5	Myocardin	Myocd	LIG_Actin_RPEL_3	64	83	Missing in isoform 2, 4, 5	view
Q8VIM5	Myocardin	Myocd	LIG_Actin_RPEL_3	108	127	Missing in isoform 2	view
Q13268	Dehydrogenase/reductase SDR family member 2	DHRS2	LIG_PDZ_Class_1	253	258	Missing in isoform 2	view
Q9Y618	Nuclear receptor corepressor 2	NCOR2	LIG_WW_Pin1_4	1238	1243	Missing in isoform 2	view
Q9Y618	Nuclear receptor corepressor 2	NCOR2	LIG_WW_Pin1_4	1441	1446	Missing in isoform 2	view
Q9UBS5	Gamma-aminobutyric acid type B receptor subunit 1	GABBR1	TRG_ER_diArg_1	923	926	Missing in isoform 1E, 1D	view
Q86UR1	NADPH oxidase activator 1	NOXA1	MOD_PKA_1	169	175	Missing in isoform 3	view
P29590	Protein PML	PML	LIG_WW_Pin1_4	502	507	Missing in isoform PML-14, PML-7	view
P29590	Protein PML	PML	LIG_WW_Pin1_4	524	529	Missing in isoform PML-14, PML-7	view
P29590	Protein PML	PML	LIG_WW_Pin1_4	515	520	Missing in isoform PML-14, PML-7	view
P00533	Epidermal growth factor receptor	EGFR	LIG_SH2_SRC	1016	1019	Missing in isoform 2, 4, 3	view
P00533	Epidermal growth factor receptor	EGFR	LIG_SH2_SRC	1125	1128	Missing in isoform 2, 4, 3	view
P00533	Epidermal growth factor receptor	EGFR	TRG_ENDOCYTIC_2	998	1001	Missing in isoform 2, 4, 3	view
P00533	Epidermal growth factor receptor	EGFR	LIG_PTB_Phospho_1	1104	1110	Missing in isoform 2, 4, 3	view
P02751	Fibronectin	FN1	LIG_RGD	1524	1526	Missing in isoform 2	view
P02751	Fibronectin	FN1	LIG_Integrin_isoDGR_1	367	369	Missing in isoform 2	view
P02751	Fibronectin	FN1	LIG_Integrin_isoDGR_1	1432	1434	Missing in isoform 2, 12	view
P47902	Homeobox protein CDX-1	CDX1	LIG_HOMEOBOX	133	136	Missing in isoform 2	view
P35222	Catenin beta-1	CTNNB1	LIG_SCF-TrCP1_1	32	37	Missing in isoform 2	view
P35222	Catenin beta-1	CTNNB1	MOD_PKA_1	549	555	Missing in isoform 2	view
P35222	Catenin beta-1	CTNNB1	MOD_PKA_1	672	678	Missing in isoform 2	view
P35222	Catenin beta-1	CTNNB1	LIG_PDZ_Class_1	776	781	Missing in isoform 2	view
P35222	Catenin beta-1	CTNNB1	LIG_WW_Pin1_4	243	248	Missing in isoform 2	view
Q9NWV8	BRISC and BRCA1-A complex member 1	BABAM1	LIG_TNKBM_1	27	34	Missing in isoform 2	view
Q9NWV8	BRISC and BRCA1-A complex member 1	BABAM1	LIG_TNKBM_1	47	54	Missing in isoform 2	view
Q01860	POU domain, class 5, transcription factor 1	POU5F1	LIG_WW_Pin1_4	9	14	Missing in isoform B	view
O75553	Disabled homolog 1	DAB1	LIG_SIAH_1	360	368	Missing in isoform DAB213	view
P49137	MAP kinase-activated protein kinase 2	MAPKAPK2	TRG_NES_CRM1_1	354	368	Missing in isoform 2	view
Q8TEU7	Rap guanine nucleotide exchange factor 6	RAPGEF6	LIG_PDZ_Class_1	1596	1601	Missing in isoform 2	view
Q13136	Liprin-alpha-1	PPFIA1	LIG_PDZ_Class_2	1197	1202	Missing in isoform 2	view
P16410	Cytotoxic T-lymphocyte protein 4	CTLA4	TRG_ENDOCYTIC_2	201	204	Missing in isoform 2, 3, 4	view
P04637	Cellular tumor antigen p53	TP53	LIG_CYCLIN_1	381	385	Missing in isoform 2, 5, 8, 3, 6, 9	view
P04637	Cellular tumor antigen p53	TP53	MOD_SUMO	385	388	Missing in isoform 2, 5, 8, 3, 6, 9	view
P04637	Cellular tumor antigen p53	TP53	LIG_MDM2	19	26	Missing in isoform 7, 8, 9, 4, 5, 6	view
P04637	Cellular tumor antigen p53	TP53	TRG_NES_CRM1_1	339	352	Missing in isoform 3, 6, 9, 2, 5, 8, 2, 5, 8, 3, 6, 9	view
P04637	Cellular tumor antigen p53	TP53	MOD_PIKK_1	12	18	Missing in isoform 7, 8, 9, 4, 5, 6	view
P04637	Cellular tumor antigen p53	TP53	LIG_USP7_1	359	363	Missing in isoform 2, 5, 8, 3, 6, 9	view
P04637	Cellular tumor antigen p53	TP53	LIG_USP7_1	364	368	Missing in isoform 2, 5, 8, 3, 6, 9	view
P04637	Cellular tumor antigen p53	TP53	MOD_GSK3_1	30	37	Missing in isoform 7, 8, 9, 4, 5, 6	view
P04637	Cellular tumor antigen p53	TP53	LIG_WW_Pin1_4	30	35	Missing in isoform 7, 8, 9, 4, 5, 6	view
P04637	Cellular tumor antigen p53	TP53	LIG_WW_Pin1_4	78	83	Missing in isoform 7, 8, 9	view
O54918	Bcl-2-like protein 11	Bcl2l11	LIG_WW_Pin1_4	62	67	Missing in isoform BimS, BimL	view
Q12955	Ankyrin-3	ANK3	LIG_EVH1_1	3254	3259	Missing in isoform 2, 3	view
Q9UHK6	Alpha-methylacyl-CoA racemase	AMACR	TRG_PTS1	379	382	Missing in isoform 3, 2	view
P14598	Neutrophil cytosol factor 1	NCF1	LIG_SH3_2	363	368	Missing in isoform 2	view
P14598	Neutrophil cytosol factor 1	NCF1	LIG_WW_Pin1_4	342	347	Missing in isoform 2	view
P22303	Acetylcholinesterase	ACHE	MOD_N-GLC_1	380	385	Missing in isoform 4	view
P22307	Non-specific lipid-transfer protein	SCP2	TRG_PTS1	544	547	Missing in isoform 3	view
P37088	Amiloride-sensitive sodium channel subunit alpha	SCNN1A	LIG_WW_1	641	644	Missing in isoform 3	view
Q08877	Dynamin-3	Dnm3	LIG_EVH1_2	809	813	Missing in isoform 13	view
P18206	Vinculin	VCL	LIG_EVH1_1	842	847	Missing in isoform 3	view
P03254	Early E1A 32 kDa protein	None	LIG_CtBP_PxDLS_1	279	283	Missing in isoform early	view
P35240	Merlin	NF2	MOD_PKA_1	515	521	Missing in isoform 9, 7, 10	view
Q9JL19	Nuclear receptor coactivator 6	Ncoa6	LIG_NRBOX	1494	1500	Missing in isoform 2	view
P10676	Neither inactivation nor afterpotential protein C	ninaC	LIG_IQ	1073	1091	Missing in isoform A	view
O14757	Serine/threonine-protein kinase Chk1	CHEK1	LIG_BIR_III_1	1	5	Missing in isoform 2	view
Q05586	Glutamate [NMDA] receptor subunit zeta-1	GRIN1	TRG_ER_diArg_1	893	895	Missing in isoform 2, 1	view
Q05586	Glutamate [NMDA] receptor subunit zeta-1	GRIN1	MOD_PKA_1	894	900	Missing in isoform 2, 1	view
Q14934	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	MOD_ProDKin_1	165	171	Missing in isoform 22, 23, 24, 19, 20, 21	view
Q14934	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	MOD_ProDKin_1	167	173	Missing in isoform 22, 23, 24, 19, 20, 21	view
Q9BZW8	Natural killer cell receptor 2B4	CD244	MOD_TYR_ITSM	338	345	Missing in isoform 3	view
P51617	Interleukin-1 receptor-associated kinase 1	IRAK1	LIG_TRAF6	540	548	Missing in isoform 2, 3	view
P19491	Glutamate receptor 2	Gria2	LIG_PDZ_Class_2	878	883	Missing in isoform 3	view
P16070	CD44 antigen	CD44	TRG_LysEnd_APsAcLL_1	708	713	Missing in isoform 2, 19, 9, 15	view
P17612	cAMP-dependent protein kinase catalytic subunit alpha	PRKACA	MOD_NMyristoyl	1	7	Missing in isoform 2	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1	LIG_PP1	896	902	Missing in isoform 5, 3, 6	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1	TRG_NLS_MonoExtN_4	606	611	Missing in isoform 5, 3, 6	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1	TRG_NLS_MonoExtN_4	501	508	Missing in isoform 5, 3, 6	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1	TRG_NLS_MonoExtC_3	502	507	Missing in isoform 5, 3, 6	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1	TRG_NLS_MonoCore_2	502	507	Missing in isoform 5, 3, 6	view
Q13492	Phosphatidylinositol-binding clathrin assembly protein	PICALM	LIG_EH_1	436	440	Missing in isoform 3	view
P0C205	Protein Rex	None	TRG_NLS_MonoExtC_3	12	17	Missing in isoform p21Rex	view
P28324	ETS domain-containing protein Elk-4	ELK4	LIG_MAPK_2	398	401	Missing in isoform 2	view
P28324	ETS domain-containing protein Elk-4	ELK4	MOD_ProDKin_1	378	384	Missing in isoform 2	view
P28324	ETS domain-containing protein Elk-4	ELK4	MOD_ProDKin_1	384	390	Missing in isoform 2	view
P25942	Tumor necrosis factor receptor superfamily member 5	CD40	LIG_TRAF6	231	239	Missing in isoform II	view
P25942	Tumor necrosis factor receptor superfamily member 5	CD40	LIG_TRAF2_1	250	253	Missing in isoform II	view
Q9Y543	Transcription factor HES-2	HES2	LIG_WRPW_1	170	173	Missing in isoform 2	view
P08621	U1 small nuclear ribonucleoprotein 70 kDa	SNRNP70	CLV_C14_Caspase3-7	338	342	Missing in isoform 3	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	LIG_SH2_STAT3	767	770	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	LIG_SH2_STAT3	814	817	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	LIG_SH2_STAT3	905	908	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	LIG_SH2_STAT3	915	918	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	MOD_N-GLC_1	378	383	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	MOD_N-GLC_1	382	387	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	MOD_N-GLC_1	552	557	Missing in isoform 2	view
P40189	Interleukin-6 receptor subunit beta	IL6ST	MOD_N-GLC_1	563	568	Missing in isoform 2	view
P00523	Proto-oncogene tyrosine-protein kinase Src	SRC	MOD_TYR_CSK	523	531	Missing in isoform 2	view
Q9Y2N7	Hypoxia-inducible factor 3-alpha	HIF3A	LIG_ODPH_VHL_1	490	502	Missing in isoform 6, 4	view
Q9UD71	Protein phosphatase 1 regulatory subunit 1B	PPP1R1B	LIG_PP1	5	12	Missing in isoform 2	view
Q15303	Receptor tyrosine-protein kinase erbB-4	ERBB4	LIG_WW_1	1053	1056	Missing in isoform JM-A, JM-B	view
Q15303	Receptor tyrosine-protein kinase erbB-4	ERBB4	LIG_SH2_STAT5	1056	1059	Missing in isoform JM-A, JM-B	view
Q8K4J6	MKL/myocardin-like protein 1	Mkl1	LIG_Actin_RPEL_3	17	36	Missing in isoform 2	view
Q99062	Granulocyte colony-stimulating factor receptor	CSF3R	LIG_SH2_STAT3	727	730	Missing in isoform 2	view
Q06124	Tyrosine-protein phosphatase non-receptor type 11	PTPN11	LIG_SH2_GRB2	546	549	Missing in isoform 3	view
P03138	Large envelope protein	S	MOD_NMyristoyl	1	7	Missing in isoform S, M	view
Q9UJY5	ADP-ribosylation factor-binding protein GGA1	GGA1	TRG_LysEnd_GGAAcLL_2	355	362	Missing in isoform 5, 4	view
P17542	T-cell acute lymphocytic leukemia protein 1	TAL1	MOD_ProDKin_1	119	125	Missing in isoform PP22-TAL1	view
Q9C0C2	182 kDa tankyrase-1-binding protein	TNKS1BP1	LIG_TNKBM_1	1507	1514	Missing in isoform 2	view
Q9Y458	T-box transcription factor TBX22	TBX22	LIG_EH1_1	9	17	Missing in isoform 2	view
Q04656	Copper-transporting ATPase 1	ATP7A	TRG_LysEnd_APsAcLL_1	1483	1488	Missing in isoform 6	view
P49768	Presenilin-1	PSEN1	LIG_PDZ_Class_2	462	467	Missing in isoform 4, 3, 5	view
Q6PGN9	Proline/serine-rich coiled-coil protein 1	PSRC1	LIG_SxIP_EBH_1	276	289	Missing in isoform B	view
Q9WTK7	Serine/threonine-protein kinase STK11	Stk11	MOD_PKA_1	428	434	Missing in isoform 2	view
P13051	Uracil-DNA glycosylase	UNG	LIG_PCNA_PIPBox_1	4	13	Missing in isoform 1	view
Q16512	Serine/threonine-protein kinase N1	PKN1	LIG_AGCK_PIF_2	932	937	Missing in isoform 3	view
P05556	Integrin beta-1	ITGB1	LIG_PTB_Apo_2	777	784	Missing in isoform Beta-1B, Beta-1C, Beta-1C-2, Beta-1D	view
P05556	Integrin beta-1	ITGB1	LIG_PTB_Apo_2	789	796	Missing in isoform Beta-1B, Beta-1C, Beta-1C-2, Beta-1D	view
Q8C2B3	Histone deacetylase 7	Hdac7	LIG_CtBP_PxDLS_1	22	26	Missing in isoform 2, 3, 5	view
O43521	Bcl-2-like protein 11	BCL2L11	LIG_Dynein_DLC8_1	110	116	Missing in isoform BimA, BimS, Bim-, Bim-alpha6, Bim-alpha4, Bim-beta4	view
Q96BK5	PIN2/TERF1-interacting telomerase inhibitor 1	PINX1	LIG_TRFH_1	289	293	Missing in isoform 2	view
Q05655	Protein kinase C delta type	PRKCD	CLV_C14_Caspase3-7	326	330	Missing in isoform 2	view
Q14511	Enhancer of filamentation 1	NEDD9	LIG_SH2_SRC	629	632	Missing in isoform 2	view
Q9JLU4	SH3 and multiple ankyrin repeat domains protein 3	Shank3	LIG_EVH1_2	1385	1389	Missing in isoform 3	view
P19235	Erythropoietin receptor	EPOR	LIG_SH2_STAT5	426	429	Missing in isoform EPOR-S, EPOR-T	view
P19235	Erythropoietin receptor	EPOR	LIG_SH2_STAT5	368	371	Missing in isoform EPOR-S, EPOR-T	view
Q9WTU3	Sodium channel protein type 8 subunit alpha	Scn8a	LIG_IQ	1894	1913	Missing in isoform 4	view
Q13367	AP-3 complex subunit beta-2	AP3B2	LIG_Clathr_ClatBox_1	808	812	Missing in isoform 2	view
Q16478	Glutamate receptor, ionotropic kainate 5	GRIK5	TRG_ER_diArg_1	862	865	Missing in isoform 2	view
P10242	Transcriptional activator Myb	MYB	MOD_SUMO	502	505	Missing in isoform 3, 5	view
P10242	Transcriptional activator Myb	MYB	MOD_SUMO	526	529	Missing in isoform 3, 5	view
P49023	Paxillin	PXN	LIG_SH2_SRC	40	43	Missing in isoform 4	view
P03070	Large T antigen	None	TRG_NLS_MonoCore_2	127	132	Missing in isoform 17kT	view
P03070	Large T antigen	None	TRG_NLS_MonoExtC_3	127	133	Missing in isoform 17kT	view
P03070	Large T antigen	None	TRG_NLS_MonoExtN_4	126	132	Missing in isoform 17kT	view
P03070	Large T antigen	None	LIG_SCF_FBW7_2	699	705	Missing in isoform 17kT	view
Q62910	Synaptojanin-1	Synj1	LIG_EH_1	1400	1404	Missing in isoform 2, 5	view
Q62910	Synaptojanin-1	Synj1	LIG_EH_1	1409	1413	Missing in isoform 2, 5	view
Q62910	Synaptojanin-1	Synj1	LIG_EH_1	1420	1424	Missing in isoform 2, 5	view
Q925J9	Mediator of RNA polymerase II transcription subunit 1	Med1	MOD_ProDKin_1	1439	1445	Missing in isoform 3, 2	view
Q03001	Dystonin	DST	LIG_SxIP_EBH_1	7545	7558	Missing in isoform 6, 7, 8, 3, 4, 5	view
P54830	Tyrosine-protein phosphatase non-receptor type 5	Ptpn5	MOD_PKA_1	157	163	Missing in isoform STEP20, STEP46	view
Q96J92	Serine/threonine-protein kinase WNK4	WNK4	LIG_SPAK-OSR1_1	1016	1020	Missing in isoform 2	view
Q99700	Ataxin-2	ATXN2	LIG_PAM2_1	912	924	Missing in isoform 3	view
Q01344	Interleukin-5 receptor subunit alpha	IL5RA	LIG_PDZ_Class_1	415	420	Missing in isoform 3, 2	view
O14746	Telomerase reverse transcriptase	TERT	MOD_PKB_1	819	827	Missing in isoform 2	view
Q01196	Runt-related transcription factor 1	RUNX1	LIG_WRPW_1	450	453	Missing in isoform AML-1FB, AML-1FA, AML-1FC, AML-1C, AML-1E, AML-1A	view
P19419	ETS domain-containing protein Elk-1	ELK1	LIG_MAPK_1	312	321	Missing in isoform 2	view
P19419	ETS domain-containing protein Elk-1	ELK1	LIG_MAPK_2	395	398	Missing in isoform 2	view
O55012	Phosphatidylinositol-binding clathrin assembly protein	Picalm	LIG_EH_1	429	433	Missing in isoform 2	view
P30307	M-phase inducer phosphatase 3	CDC25C	LIG_APCC_KENbox_2	150	154	Missing in isoform 2, 5	view
Q9U1K1	Protein spire	spir	LIG_Actin_WH2_2	400	417	Missing in isoform C	view
Q9U1K1	Protein spire	spir	LIG_Actin_WH2_2	370	386	Missing in isoform C	view
Q9U1K1	Protein spire	spir	LIG_Actin_WH2_2	432	448	Missing in isoform C	view
Q9U1K1	Protein spire	spir	LIG_Actin_WH2_1	464	480	Missing in isoform C	view
P26358	DNA (cytosine-5)-methyltransferase 1	DNMT1	LIG_PCNA_PIPBox_1	164	173	Missing in isoform 3	view
P12371	High affinity immunoglobulin epsilon receptor subunit alpha	Fcer1a	TRG_ER_diLys_1	242	245	Missing in isoform 2	view
P20333	Tumor necrosis factor receptor superfamily member 1B	TNFRSF1B	LIG_TRAF2_1	424	427	Missing in isoform 2	view
P27512	Tumor necrosis factor receptor superfamily member 5	Cd40	LIG_TRAF6	235	243	Missing in isoform II, IV, III	view
P34152	Focal adhesion kinase 1	Ptk2	LIG_SH3_2	750	755	Missing in isoform 8, 7	view
P34152	Focal adhesion kinase 1	Ptk2	LIG_SH2_SRC	428	431	Missing in isoform 9, 8	view
P34152	Focal adhesion kinase 1	Ptk2	LIG_WW_Pin1_4	928	933	Missing in isoform 8, 7	view
P34152	Focal adhesion kinase 1	Ptk2	MOD_ProDKin_1	928	934	Missing in isoform 8, 7	view
P16144	Integrin beta-4	ITGB4	LIG_PTB_Phospho_1	1590	1596	Missing in isoform Beta-4E	view
Q08775	Runt-related transcription factor 2	Runx2	LIG_WRPW_1	604	607	Missing in isoform 4, 8, 9, 7	view
P03255	Early E1A 32 kDa protein	None	TRG_NLS_MonoExtC_3	284	289	Missing in isoform early	view
P03255	Early E1A 32 kDa protein	None	TRG_NLS_MonoCore_2	284	289	Missing in isoform early	view
P03255	Early E1A 32 kDa protein	None	LIG_Rb_pABgroove_1	41	49	Missing in isoform early	view
P03255	Early E1A 32 kDa protein	None	LIG_Rb_LxCxE_1	122	126	Missing in isoform early	view
Q12972	Nuclear inhibitor of protein phosphatase 1	PPP1R8	LIG_PP1	198	204	Missing in isoform Gamma	view
Q9H251	Cadherin-23	CDH23	LIG_PDZ_Class_1	3349	3354	Missing in isoform 5, 6	view
P50542	Peroxisomal targeting signal 1 receptor	PEX5	TRG_PEX	243	247	Missing in isoform 2	view
P16871	Interleukin-7 receptor subunit alpha	IL7R	LIG_SH2_STAT5	449	452	Missing in isoform 4, 2, 3	view
P23634	Plasma membrane calcium-transporting ATPase 4	ATP2B4	LIG_PDZ_Class_1	1236	1241	Missing in isoform XA, XK, ZA, ZK	view
P24394	Interleukin-4 receptor subunit alpha	IL4R	LIG_SH2_STAT6	602	606	Missing in isoform 2	view
P24394	Interleukin-4 receptor subunit alpha	IL4R	LIG_PTB_Phospho_1	491	497	Missing in isoform 2	view
O15350	Tumor protein p73	TP73	LIG_SH3_3	407	413	Missing in isoform Zeta, Gamma, dN-Gamma, Epsilon, Delta	view
O15350	Tumor protein p73	TP73	LIG_MDM2	15	22	Missing in isoform dN-Alpha, dN-Beta, dN-Gamma	view
O15350	Tumor protein p73	TP73	LIG_WW_Pin1_4	409	414	Missing in isoform Zeta, Gamma, dN-Gamma, Epsilon, Delta	view
O15350	Tumor protein p73	TP73	LIG_WW_Pin1_4	439	444	Missing in isoform Zeta, Gamma, dN-Gamma, Epsilon, Delta	view
O15350	Tumor protein p73	TP73	LIG_WW_Pin1_4	479	484	Missing in isoform Zeta, Delta, Epsilon, Gamma, dN-	view
P27782	Lymphoid enhancer-binding factor 1	Lef1	MOD_SUMO	24	27	Missing in isoform 2	view
Q63943	Myocyte-specific enhancer factor 2D	Mef2d	MOD_PKA_1	118	124	Missing in isoform Muscle	view
Q9Y6H5	Synphilin-1	SNCAIP	LIG_WW_Pin1_4	208	213	Missing in isoform 2, 5	view
Q9Y6H5	Synphilin-1	SNCAIP	LIG_WW_Pin1_4	212	217	Missing in isoform 2, 5	view
Q924N4	Solute carrier family 12 member 6	Slc12a6	LIG_SPAK-OSR1_1	14	18	Missing in isoform 2	view
O60716	Catenin delta-1	CTNND1	TRG_NES_CRM1_1	942	956	Missing in isoform 1AC, 1A, 1C, 1, 2AC, 2A, 2C, 2, 3AC, 3A, 3C, 3, 4AC, 4A, 4C, 4	view
Q9UBP0	Spastin	SPAST	TRG_NLS_MonoExtN_4	7	13	Missing in isoform 3, 4	view
Q9UIB8	SLAM family member 5	CD84	MOD_TYR_ITSM	275	282	Missing in isoform 6, 4, 5, 4	view
Q9UIB8	SLAM family member 5	CD84	MOD_TYR_ITSM	312	319	Missing in isoform 6, 5, 4	view
O95644	Nuclear factor of activated T-cells, cytoplasmic 1	NFATC1	LIG_KEPE_2	701	708	Missing in isoform A-alpha, A-alpha', A-beta	view
O95644	Nuclear factor of activated T-cells, cytoplasmic 1	NFATC1	LIG_KEPE_2	913	921	Missing in isoform A-alpha, A-, A-beta, B-alpha, B-beta	view
P01112	GTPase HRas	HRAS	MOD_SPalmitoyl_2	180	186	Missing in isoform 2	view