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Predicted switches in the ELMs Resource


General :OverviewVisualisationStatistics

Subsets

Avidity : Avidity-sensing

Specificity : Altered binding specificityCompetitionDomain hidingMotif hiding

Cumulative : Rheostatic

Pre-assembly : Composite binding site formation

Binary : AllosteryPhysicochemical compatibilityPre-translationalDefinedPTM-induced


Pre-assembly - Composite binding site formation

The formation of a complex results in the generation of a continuous motif-binding site that spans more than one component of this complex. Neither complex subunit on its own contains a functional binding domain for the motif, and interaction of the motif only occurs in the context of the active, fully assembled complex.

AccessionProteinGeneMotifStartStopVis
P17495Disintegrin trigramin-beta-2NoneLIG_RGD5153view
P35555Fibrillin-1FBN1LIG_Integrin_isoDGR_123042306view
P49919Cyclin-dependent kinase inhibitor 1CCdkn1cLIG_SCF_Skp2-Cks1_1338345view
P49918Cyclin-dependent kinase inhibitor 1CCDKN1CLIG_SCF_Skp2-Cks1_1306313view
P62384Disintegrin albolabrinNoneLIG_RGD5153view
P21404Genome polyproteinNoneLIG_RGD858860view
P04004VitronectinVTNLIG_RGD6466view
P21815Bone sialoprotein 2IBSPLIG_RGD286288view
P02887Discoidin-1 subunit B/CdscC-1LIG_RGD7981view
P03305Genome polyproteinNoneLIG_RGD869871view
P31096OsteopontinSPP1LIG_RGD152154view
P02751FibronectinFN1LIG_RGD15241526view
P02751FibronectinFN1LIG_Integrin_isoDGR_1263265view
P02751FibronectinFN1LIG_Integrin_isoDGR_1367369view
P02751FibronectinFN1LIG_Integrin_isoDGR_1501503view
P02751FibronectinFN1LIG_Integrin_isoDGR_114321434view
Q66578Genome polyproteinNoneLIG_RGD764766view
P29788VitronectinVtnLIG_RGD6466view
P04275von Willebrand factorVWFLIG_RGD698700view
P04275von Willebrand factorVWFLIG_RGD25072509view
P46527Cyclin-dependent kinase inhibitor 1BCDKN1BLIG_SCF_Skp2-Cks1_1183190view
P10451OsteopontinSPP1LIG_RGD159161view
O43854EGF-like repeat and discoidin I-like domain-containing protein 3EDIL3LIG_RGD9698view
P13839Bone sialoprotein 2IbspLIG_RGD289291view
P17349Zinc metalloproteinase/disintegrinNoneLIG_RGD459461view
P03276Penton proteinPIIILIG_RGD340342view
P11276FibronectinFn1LIG_RGD21812183view
P11276FibronectinFn1LIG_RGD16141616view
P11276FibronectinFn1LIG_Integrin_isoDGR_1264266view
P11276FibronectinFn1LIG_Integrin_isoDGR_1501503view
P08721OsteopontinSpp1LIG_RGD144146view
           
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