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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: ELM:LIG_RGD (63 hits) x
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x  Coloured by: Pathway evidence source
          Curated          inferred


x  Index
ECM-receptor interactionECM-receptor interactionFocal adhesion
Focal adhesionHematopoietic cell lineagePI3K-Akt signaling pathway
PI3K-Akt signaling pathwayPhagosomePhagosome
Regulation of actin cytoskeletonRegulation of actin cytoskeleton


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

ECM-receptor interaction (KEGG - hsa04512)
LIG_RGD EDIL3_HUMAN9698Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISG_TRIAB5153Pre‑assemblyComposite binding site formationBinding of Disintegrin albolabrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_FMDVO869871Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_HUMAN6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (VTN) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VWF_HUMAN25072509Pre‑assemblyComposite binding site formationBinding of von Willebrand factor (VWF) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD OSTP_HUMAN159161Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VME1_TRIEL459461Pre‑assemblyComposite binding site formationBinding of Zinc metalloproteinase/disintegrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISB_TRIGA5153Pre‑assemblyComposite binding site formationBinding of Disintegrin trigramin-beta-2 to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_CXA9858860Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_HPE1H764766Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

ECM-receptor interaction (KEGG - mmu04512)
LIG_RGD FINC_MOUSE16141616Pre‑assemblyComposite binding site formationBinding of Fibronectin (Fn1) to integrin receptors depends on pre-assembly of Integrin alpha-5 (Itga5)-Integrin beta-1 (Itgb1) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_MOUSE6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (Vtn) to integrin receptors depends on pre-assembly of Integrin alpha-V (Itgav)-Integrin beta-3 (Itgb3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Focal adhesion (KEGG - hsa04510)
LIG_RGD EDIL3_HUMAN9698Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISG_TRIAB5153Pre‑assemblyComposite binding site formationBinding of Disintegrin albolabrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_FMDVO869871Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_HUMAN6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (VTN) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VWF_HUMAN25072509Pre‑assemblyComposite binding site formationBinding of von Willebrand factor (VWF) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD OSTP_HUMAN159161Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VME1_TRIEL459461Pre‑assemblyComposite binding site formationBinding of Zinc metalloproteinase/disintegrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISB_TRIGA5153Pre‑assemblyComposite binding site formationBinding of Disintegrin trigramin-beta-2 to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_CXA9858860Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_HPE1H764766Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Focal adhesion (KEGG - mmu04510)
LIG_RGD FINC_MOUSE16141616Pre‑assemblyComposite binding site formationBinding of Fibronectin (Fn1) to integrin receptors depends on pre-assembly of Integrin alpha-5 (Itga5)-Integrin beta-1 (Itgb1) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_MOUSE6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (Vtn) to integrin receptors depends on pre-assembly of Integrin alpha-V (Itgav)-Integrin beta-3 (Itgb3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Hematopoietic cell lineage (KEGG - hsa04640)
LIG_RGD DISG_TRIAB5153Pre‑assemblyComposite binding site formationBinding of Disintegrin albolabrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VME1_TRIEL459461Pre‑assemblyComposite binding site formationBinding of Zinc metalloproteinase/disintegrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISB_TRIGA5153Pre‑assemblyComposite binding site formationBinding of Disintegrin trigramin-beta-2 to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

PI3K-Akt signaling pathway (KEGG - hsa04151)
LIG_RGD EDIL3_HUMAN9698Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISG_TRIAB5153Pre‑assemblyComposite binding site formationBinding of Disintegrin albolabrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_FMDVO869871Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_HUMAN6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (VTN) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VWF_HUMAN25072509Pre‑assemblyComposite binding site formationBinding of von Willebrand factor (VWF) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD OSTP_HUMAN159161Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VME1_TRIEL459461Pre‑assemblyComposite binding site formationBinding of Zinc metalloproteinase/disintegrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISB_TRIGA5153Pre‑assemblyComposite binding site formationBinding of Disintegrin trigramin-beta-2 to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_CXA9858860Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_HPE1H764766Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

PI3K-Akt signaling pathway (KEGG - mmu04151)
LIG_RGD FINC_MOUSE16141616Pre‑assemblyComposite binding site formationBinding of Fibronectin (Fn1) to integrin receptors depends on pre-assembly of Integrin alpha-5 (Itga5)-Integrin beta-1 (Itgb1) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_MOUSE6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (Vtn) to integrin receptors depends on pre-assembly of Integrin alpha-V (Itgav)-Integrin beta-3 (Itgb3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Phagosome (KEGG - hsa04145)
LIG_RGD EDIL3_HUMAN9698Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_FMDVO869871Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_HUMAN6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (VTN) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VWF_HUMAN25072509Pre‑assemblyComposite binding site formationBinding of von Willebrand factor (VWF) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD OSTP_HUMAN159161Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Phagosome (KEGG - mmu04145)
LIG_RGD FINC_MOUSE16141616Pre‑assemblyComposite binding site formationBinding of Fibronectin (Fn1) to integrin receptors depends on pre-assembly of Integrin alpha-5 (Itga5)-Integrin beta-1 (Itgb1) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_MOUSE6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (Vtn) to integrin receptors depends on pre-assembly of Integrin alpha-V (Itgav)-Integrin beta-3 (Itgb3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Regulation of actin cytoskeleton (KEGG - hsa04810)
LIG_RGD EDIL3_HUMAN9698Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISG_TRIAB5153Pre‑assemblyComposite binding site formationBinding of Disintegrin albolabrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD FINC_HUMAN15241526Pre‑assemblyComposite binding site formationBinding of Fibronectin (FN1) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_FMDVO869871Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_HUMAN6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (VTN) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VWF_HUMAN25072509Pre‑assemblyComposite binding site formationBinding of von Willebrand factor (VWF) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD OSTP_HUMAN159161Pre‑assemblyComposite binding site formationBinding of EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VME1_TRIEL459461Pre‑assemblyComposite binding site formationBinding of Zinc metalloproteinase/disintegrin to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD DISB_TRIGA5153Pre‑assemblyComposite binding site formationBinding of Disintegrin trigramin-beta-2 to integrin receptors depends on pre-assembly of Integrin alpha-IIb (ITGA2B)-Integrin beta-3 (ITGB3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_CXA9858860Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD POLG_HPE1H764766Pre‑assemblyComposite binding site formationBinding of Genome polyprotein to integrin receptors depends on pre-assembly of Integrin alpha-V (ITGAV)-Integrin beta-6 (ITGB6) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred

Regulation of actin cytoskeleton (KEGG - mmu04810)
LIG_RGD FINC_MOUSE16141616Pre‑assemblyComposite binding site formationBinding of Fibronectin (Fn1) to integrin receptors depends on pre-assembly of Integrin alpha-5 (Itga5)-Integrin beta-1 (Itgb1) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
LIG_RGD VTNC_MOUSE6466Pre‑assemblyComposite binding site formationBinding of Vitronectin (Vtn) to integrin receptors depends on pre-assembly of Integrin alpha-V (Itgav)-Integrin beta-3 (Itgb3) heterodimers, since association of the integrin alpha and beta subunits results in the formation of a composite binding site for the RGD motif in the ligand.
details
Inferred
           
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