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Group by :Switch typeMotif classProteinEnzymePathway         Hide inferred   Group Index    Colouring Info              Filtered: ELM:LIG_SH2_IC (20 hits) x
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x  Coloured by: Modifier evidence source
          Curated          inferred


x  Index
Epidermal growth factor receptorHepatocyte growth factor receptorInsulin-like growth factor 1 receptor
Macrophage-stimulating protein receptorNeuronal proto-oncogene tyrosine-protein kinase Src (Mus)Proto-oncogene tyrosine-protein kinase Src
Receptor tyrosine-protein kinase erbB-2Tyrosine-protein kinase ABL1Tyrosine-protein kinase SYK
Tyrosine-protein kinase ZAP-70Vascular endothelial growth factor receptor 3


MotifProteinStartEndSwitch TypeSwitch SubtypeSwitch descriptionInformationEvidence

Epidermal growth factor receptor - EGFR -  Homo sapiens
LIG_SH2_IC EGFR_HUMAN10921100BinaryPhysicochemical compatibilityPhosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC EGFR_HUMAN10921100BinaryPhysicochemical compatibilityPhosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Hepatocyte growth factor receptor - MET -  Homo sapiens
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC SHC1_HUMAN423435BinaryPhysicochemical compatibilityPhosphorylation of Y427 in the SH2-binding motif of SHC-transforming protein 1 (SHC1) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Insulin-like growth factor 1 receptor - IGF1R -  Homo sapiens
LIG_SH2_IC PDPK1_HUMAN376379BinaryPhysicochemical compatibilityPhosphorylation of Y376 in the SH2-binding motif of 3-phosphoinositide-dependent protein kinase 1 (PDPK1) induces binding to the Tensin-1 (TNS1) protein.
details
Inferred

Macrophage-stimulating protein receptor - MST1R -  Homo sapiens
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Neuronal proto-oncogene tyrosine-protein kinase Src - SRC -  Mus musculus
LIG_SH2_IC EGFR_HUMAN10921100BinaryPhysicochemical compatibilityPhosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Proto-oncogene tyrosine-protein kinase Src - SRC -  Homo sapiens
LIG_SH2_IC PDPK1_HUMAN376379BinaryPhysicochemical compatibilityPhosphorylation of Y376 in the SH2-binding motif of 3-phosphoinositide-dependent protein kinase 1 (PDPK1) induces binding to the Tensin-1 (TNS1) protein.
details
Inferred
LIG_SH2_IC PDPK1_HUMAN376379BinaryPhysicochemical compatibilityPhosphorylation of Y376 in the SH2-binding motif of 3-phosphoinositide-dependent protein kinase 1 (PDPK1) induces binding to the Tensin-1 (TNS1) protein.
details
Inferred
LIG_SH2_IC SHC1_HUMAN423435BinaryPhysicochemical compatibilityPhosphorylation of Y427 in the SH2-binding motif of SHC-transforming protein 1 (SHC1) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Receptor tyrosine-protein kinase erbB-2 - ERBB2 -  Homo sapiens
LIG_SH2_IC ERBB2_HUMAN11351144BinaryPhysicochemical compatibilityPhosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Growth factor receptor-bound protein 7 (GRB7) protein.
details
Inferred
LIG_SH2_IC ERBB2_HUMAN11351144BinaryPhysicochemical compatibilityPhosphorylation of Y1139 in the SH2-binding motif of Receptor tyrosine-protein kinase erbB-2 (ERBB2) induces binding to the Growth factor receptor-bound protein 7 (GRB7) protein.
details
Inferred

Tyrosine-protein kinase ABL1 - ABL1 -  Homo sapiens
LIG_SH2_IC EGFR_HUMAN10921100BinaryPhysicochemical compatibilityPhosphorylation of Y1092 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
LIG_SH2_IC MET_HUMAN13511360BinaryPhysicochemical compatibilityPhosphorylation of Y1356 in the SH2-binding motif of Hepatocyte growth factor receptor (MET) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Tyrosine-protein kinase SYK - SYK -  Homo sapiens
LIG_SH2_IC SHC1_HUMAN423435BinaryPhysicochemical compatibilityPhosphorylation of Y427 in the SH2-binding motif of SHC-transforming protein 1 (SHC1) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Tyrosine-protein kinase ZAP-70 - ZAP70 -  Homo sapiens
LIG_SH2_IC SHC1_HUMAN423435BinaryPhysicochemical compatibilityPhosphorylation of Y427 in the SH2-binding motif of SHC-transforming protein 1 (SHC1) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred

Vascular endothelial growth factor receptor 3 - FLT4 -  Homo sapiens
LIG_SH2_IC SHC1_HUMAN423435BinaryPhysicochemical compatibilityPhosphorylation of Y427 in the SH2-binding motif of SHC-transforming protein 1 (SHC1) induces binding to the Growth factor receptor-bound protein 2 (GRB2) protein.
details
Inferred
           
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