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Filtered:
ELM:LIG_SH2_SRC (5 hits)
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Pathway evidence source
Curated
inferred
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Index
Calcium signaling pathway
ErbB signaling pathway
Motif
Protein
Start
End
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Information
Evidence
Calcium signaling pathway
(
KEGG - hsa04020
)
LIG_SH2_SRC
EGFR_HUMAN
1016
1019
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1)
.
details
Curated
ErbB signaling pathway
(
KEGG - hsa04012
)
LIG_SH2_SRC
EGFR_HUMAN
1016
1019
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1)
.
details
Curated
LIG_SH2_SRC
EGFR_HUMAN
1125
1128
Binary
Physicochemical compatibility
Phosphorylation of Y1125 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to
Adapter molecule crk (CRK)
.
details
Curated
LIG_SH2_SRC
EGFR_HUMAN
1016
1019
Binary
Physicochemical compatibility
Phosphorylation of Y1016 in the SH2-binding motif of
Epidermal growth factor receptor (EGFR)
induces binding to
Cytoplasmic protein NCK1 (NCK1)
.
details
Curated
LIG_SH2_SRC
FAK1_HUMAN
397
400
Binary
Physicochemical compatibility
Phosphorylation of Y397 in the SH2-binding motif of
Focal adhesion kinase 1 (PTK2)
induces binding to
Neuronal proto-oncogene tyrosine-protein kinase Src (Src)
.
details
Curated
