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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: PFAM:PF00533 (7 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
LIG_BRCT_BRCA1_1LIG_BRCT_BRCA1_2LIG_BRCT_MDC1_1


ProteinStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

LIG_BRCT_BRCA1_1 - Phosphopeptide motif which directly interacts with the BRCT (carboxy-terminal) domain of the Breast Cancer Gene BRCA1 with low affinity
ACACA_HUMAN12621266BinaryPhysicochemical compatibilityPhosphorylation of S1263 in the BRCT-binding motif of Acetyl-CoA carboxylase 1 (ACACA) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details
F175A_HUMAN405409BinaryPhysicochemical compatibilityPhosphorylation of S406 in the BRCT-binding motif of BRCA1-A complex subunit Abraxas (FAM175A) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details
ATRIP_HUMAN238242BinaryPhysicochemical compatibilityPhosphorylation of S239 in the BRCT-binding motif of ATR-interacting protein (ATRIP) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details
COM1_HUMAN326330BinaryPhysicochemical compatibilityPhosphorylation of S327 in the BRCT-binding motif of DNA endonuclease RBBP8 (RBBP8) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details
FANCJ_HUMAN989993BinaryPhysicochemical compatibilityPhosphorylation of S990 in the BRCT-binding motif of Fanconi anemia group J protein (BRIP1) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details

LIG_BRCT_BRCA1_2 - Phosphopeptide motif which directly interacts with the BRCT (carboxy-terminal) domain of the Breast Cancer Gene BRCA1 with high affinity.
FANCJ_HUMAN989995BinaryPhysicochemical compatibilityPhosphorylation of S990 in the BRCT-binding motif of Fanconi anemia group J protein (BRIP1) induces binding to the Breast cancer type 1 susceptibility protein (BRCA1) protein.
details

LIG_BRCT_MDC1_1 - Phosphopeptide motif which is specifically recognized by the BRCT (Carboxy-terminal) repeats of MDC1
H2AX_HUMAN139143BinaryPhysicochemical compatibilityPhosphorylation of S140 in the BRCT-binding motif of Histone H2A.x (H2AFX) induces binding to the Mediator of DNA damage checkpoint protein 1 (MDC1) protein.
details
           
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