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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: UNIPROT:P46108 (8 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
Breast cancer anti-estrogen resistance protein 1Disabled homolog 1E3 ubiquitin-protein ligase CBL
Ephrin type-B receptor 2 (Mus)Epidermal growth factor receptorPaxillin


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Breast cancer anti-estrogen resistance protein 1 - BCAR1 -  Homo sapiens
LIG_SH2_IB358368BinaryPhysicochemical compatibilityPhosphorylation of Y362 in the SH2-binding motif of Breast cancer anti-estrogen resistance protein 1 (BCAR1) induces binding to the Adapter molecule crk (CRK) protein.
details

Disabled homolog 1 - DAB1 -  Homo sapiens
LIG_SH2_IB211230BinaryPhysicochemical compatibilityPhosphorylation of Y220 in the SH2-binding motif of Disabled homolog 1 (DAB1) induces binding to the Adapter molecule crk (CRK) protein.
details

E3 ubiquitin-protein ligase CBL - CBL -  Homo sapiens
LIG_SH2_IB770780BinaryPhysicochemical compatibilityPhosphorylation of Y774 in the SH2-binding motif of E3 ubiquitin-protein ligase CBL (CBL) induces binding to the Adapter molecule crk (CRK) protein.
details

Ephrin type-B receptor 2 - Ephb2 -  Mus musculus
LIG_SH2_IB601610BinaryPhysicochemical compatibilityPhosphorylation of Y604 in the SH2-binding motif of Ephrin type-B receptor 2 (Ephb2) induces binding to the Adapter molecule crk (CRK) protein.
details
LIG_SH2_IB606620BinaryPhysicochemical compatibilityPhosphorylation of Y610 in the SH2-binding motif of Ephrin type-B receptor 2 (Ephb2) induces binding to the Adapter molecule crk (CRK) protein.
details

Epidermal growth factor receptor - EGFR -  Homo sapiens
LIG_SH2_SRC11251128BinaryPhysicochemical compatibilityPhosphorylation of Y1125 in the SH2-binding motif of Epidermal growth factor receptor (EGFR) induces binding to Adapter molecule crk (CRK).
details

Paxillin - PXN -  Homo sapiens
LIG_SH2_IB118121BinaryPre‑translationalAlternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Adapter molecule crk (CRK).
details
LIG_SH2_IB3134BinaryPre‑translationalAlternative splicing removes the SH2-binding motif of Paxillin (PXN), abrogating binding to Adapter molecule crk (CRK).
details
           
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