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Group by :Switch typeMotif classProteinEnzymePathway            Group Index    Colouring Info              Filtered: ELM:LIG_SH2_IIB (13 hits) x
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  Domain hiding  Altered binding specificity  Motif hiding  Composite binding site formation
  Uncategorised  Rheostatic  Allostery  Avidity-sensing
  Physicochemical compatibility  Pre-translational  Competition

x  Index
Docking protein 1High affinity nerve growth factor receptorInterleukin-2 receptor subunit beta
Interleukin-4 receptor subunit alphaLymphocyte cytosolic protein 2Mitogen-activated protein kinase kinase kinase kinase 1
Platelet-derived growth factor receptor alphaProto-oncogene tyrosine-protein kinase receptor RetProto-oncogene vav
Tyrosine-protein kinase JAK2


MotifStartEndSwitch TypeSwitch SubtypeSwitch DescriptionInformation

Docking protein 1 - DOK1 -  Homo sapiens
LIG_SH2_IIB203206BinaryPhysicochemical compatibilityPhosphorylation of Y203 in the SH2-binding motif of Docking protein 1 (DOK1) induces binding to the Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) protein.
details

High affinity nerve growth factor receptor - NTRK1 -  Homo sapiens
LIG_SH2_IIB782796BinaryPhysicochemical compatibilityPhosphorylation of Y791 in the SH2-binding motif of High affinity nerve growth factor receptor (NTRK1) induces binding to the SHC-transforming protein 1 (SHC1) protein.
details

Interleukin-2 receptor subunit beta - IL2RB -  Homo sapiens
LIG_SH2_IIB361370BinaryPhysicochemical compatibilityPhosphorylation of Y364 in the SH2-binding motif of Interleukin-2 receptor subunit beta (IL2RB) induces binding to the SHC-transforming protein 1 (SHC1) protein.
details

Interleukin-4 receptor subunit alpha - IL4R -  Homo sapiens
LIG_SH2_IIB706721BinaryPhysicochemical compatibilityPhosphorylation of Y713 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the SHC-transforming protein 1 (SHC1) protein.
details
LIG_SH2_IIB706721BinaryPhysicochemical compatibilityPhosphorylation of Y713 in the SH2-binding motif of Interleukin-4 receptor subunit alpha (IL4R) induces binding to the Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (INPP5D) protein.
details

Lymphocyte cytosolic protein 2 - LCP2 -  Homo sapiens
LIG_SH2_IIB105118BinaryPhysicochemical compatibilityPhosphorylation of Y113 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.
details
LIG_SH2_IIB120133BinaryPhysicochemical compatibilityPhosphorylation of Y128 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.
details
LIG_SH2_IIB137150BinaryPhysicochemical compatibilityPhosphorylation of Y145 in the SH2-binding motif of Lymphocyte cytosolic protein 2 (LCP2) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.
details

Mitogen-activated protein kinase kinase kinase kinase 1 - MAP4K1 -  Homo sapiens
LIG_SH2_IIB372391BinaryPhysicochemical compatibilityPhosphorylation of Y381 in the SH2-binding motif of Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) induces binding to the B-cell linker protein (BLNK) protein.
details

Platelet-derived growth factor receptor alpha - PDGFRA -  Homo sapiens
LIG_SH2_IIB705729BinaryPhysicochemical compatibilityPhosphorylation of Y720 in the SH2-binding motif of Platelet-derived growth factor receptor alpha (PDGFRA) induces binding to the SH2 domain-containing adapter protein F (SHF) protein.
details

Proto-oncogene tyrosine-protein kinase receptor Ret - RET -  Homo sapiens
LIG_SH2_IIB976985BinaryPhysicochemical compatibilityPhosphorylation of Y981 in the SH2-binding motif of Proto-oncogene tyrosine-protein kinase receptor Ret (RET) induces binding to the SH2B adapter protein 1 (SH2B1) protein.
details

Proto-oncogene vav - VAV1 -  Homo sapiens
LIG_SH2_IIB165180BinaryPhysicochemical compatibilityPhosphorylation of Y174 in the SH2-binding motif of Proto-oncogene vav (VAV1) induces binding to the SH2 domain-containing adapter protein B (SHB) protein.
details

Tyrosine-protein kinase JAK2 - JAK2 -  Homo sapiens
LIG_SH2_IIB804823BinaryPhysicochemical compatibilityPhosphorylation of Y813 in the SH2-binding motif of Tyrosine-protein kinase JAK2 (JAK2) induces binding to the SH2B adapter protein 1 (SH2B1) protein.
details
           
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