Alpha-globin transcription factor CP2 - TFCP2 - Homo sapiens
|
| DOC_WW_Pin1_4 | 326 | 331 | Binary | Physicochemical compatibility | Phosphorylation of T329 in the Pin1-binding motif of Alpha-globin transcription factor CP2 (TFCP2) induces binding to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1), which isomerises the peptide bonds at the nearby-phosphorylated SP motifs (S291 and S309) to the trans configuration, thereby facilitating their dephosphorylation, which is required for the transcriptional activity of Alpha-globin transcription factor CP2 (TFCP2). | details |
Alpha-globin transcription factor CP2 - Tcfcp2 - Mus musculus
|
| DOC_WW_Pin1_4 | 288 | 293 | Binary | Physicochemical compatibility | Phosphorylation of S291 in the Pin1-binding motif of Alpha-globin transcription factor CP2 (Tcfcp2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 306 | 311 | Binary | Physicochemical compatibility | Phosphorylation of S309 in the Pin1-binding motif of Alpha-globin transcription factor CP2 (Tcfcp2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 326 | 331 | Binary | Physicochemical compatibility | Phosphorylation of T329 in the Pin1-binding motif of Alpha-globin transcription factor CP2 (Tcfcp2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Bcl-2-like protein 11 - Bcl2l11 - Mus musculus
|
| DOC_WW_Pin1_4 | 62 | 67 | Binary | Physicochemical compatibility | Phosphorylation of S65 in the Pin1-binding motif of Bcl-2-like protein 11 (Bcl2l11) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Beta-adrenergic receptor kinase 1 - Adrbk1 - Mus musculus
|
| DOC_WW_Pin1_4 | 667 | 672 | Binary | Physicochemical compatibility | Phosphorylation of S670 in the Pin1-binding motif of Beta-adrenergic receptor kinase 1 (Adrbk1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
CREB-regulated transcription coactivator 2 - Crtc2 - Mus musculus
|
| DOC_WW_Pin1_4 | 133 | 138 | Binary | Physicochemical compatibility | Phosphorylation of S136 in the Pin1-binding motif of CREB-regulated transcription coactivator 2 (Crtc2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Catenin beta-1 - CTNNB1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 243 | 248 | Binary | Physicochemical compatibility | Phosphorylation of S246 in the Pin1-binding motif of Catenin beta-1 (CTNNB1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Cellular tumor antigen p53 - TP53 - Homo sapiens
|
| DOC_WW_Pin1_4 | 30 | 35 | Binary | Physicochemical compatibility | Phosphorylation of S33 in the Pin1-binding motif of Cellular tumor antigen p53 (TP53) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 312 | 317 | Binary | Physicochemical compatibility | Phosphorylation of S315 in the Pin1-binding motif of Cellular tumor antigen p53 (TP53) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 78 | 83 | Binary | Physicochemical compatibility | Phosphorylation of T81 in the Pin1-binding motif of Cellular tumor antigen p53 (TP53) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Centrosomal protein of 55 kDa - Cep55 - Mus musculus
|
| DOC_WW_Pin1_4 | 420 | 425 | Binary | Physicochemical compatibility | Phosphorylation of S423 in the Pin1-binding motif of Centrosomal protein of 55 kDa (Cep55) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 423 | 428 | Binary | Physicochemical compatibility | Phosphorylation of S426 in the Pin1-binding motif of Centrosomal protein of 55 kDa (Cep55) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Cyclin-dependent kinase inhibitor 1B - CDKN1B - Homo sapiens
|
| DOC_WW_Pin1_4 | 184 | 189 | Binary | Physicochemical compatibility | Phosphorylation of T187 in the Pin1-binding motif of Cyclin-dependent kinase inhibitor 1B (CDKN1B) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Death domain-associated protein 6 - DAXX - Homo sapiens
|
| DOC_WW_Pin1_4 | 175 | 180 | Binary | Physicochemical compatibility | Phosphorylation of S178 in the Pin1-binding motif of Death domain-associated protein 6 (DAXX) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
F-box only protein 5-A - fbxo5-a - Xenopus laevis
|
| DOC_WW_Pin1_4 | 7 | 12 | Binary | Physicochemical compatibility | Phosphorylation of S10 in the Pin1-binding motif of F-box only protein 5-A (fbxo5-a) induces binding to the pin1 protein. | details |
F-box/WD repeat-containing protein 7 - FBXW7 - Homo sapiens
|
| DOC_WW_Pin1_4 | 202 | 207 | Binary | Physicochemical compatibility | Phosphorylation of T205 in the Pin1-binding motif of F-box/WD repeat-containing protein 7 (FBXW7) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. Pin1 interacts with Fbw7 in a phoshorylation-dependent manner and promotes Fbw7 self-ubiquitination and protein degradation by disrupting Fbw7 dimerization. Paper also shows the over-expression of Pin1 suppresses the ability of Fbw7 to inhibit cell transformation and proliferation, suggesting a link between Pin1 overexpression and cancer. | details |
Far upstream element-binding protein 2 - KHSRP - Homo sapiens
|
| DOC_WW_Pin1_4 | 178 | 183 | Binary | Physicochemical compatibility | Phosphorylation of S181 in the Pin1-binding motif of Far upstream element-binding protein 2 (KHSRP) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Focal adhesion kinase 1 - Ptk2 - Mus musculus
|
| DOC_WW_Pin1_4 | 907 | 912 | Binary | Physicochemical compatibility | Phosphorylation of S910 in the Pin1-binding motif of Isoform 3 of Focal adhesion kinase 1 (Ptk2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Focal adhesion kinase 1 - PTK2 - Homo sapiens
|
| DOC_WW_Pin1_4 | 907 | 912 | Binary | Physicochemical compatibility | Phosphorylation of S910 in the Pin1-binding motif of Focal adhesion kinase 1 (PTK2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
G1/S-specific cyclin-D1 - Ccnd1 - Mus musculus
|
| DOC_WW_Pin1_4 | 283 | 288 | Binary | Physicochemical compatibility | Phosphorylation of T286 in the Pin1-binding motif of G1/S-specific cyclin-D1 (Ccnd1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
G1/S-specific cyclin-E1 - Ccne1 - Mus musculus
|
| DOC_WW_Pin1_4 | 382 | 387 | Binary | Physicochemical compatibility | Phosphorylation of S385 in the Pin1-binding motif of G1/S-specific cyclin-E1 (Ccne1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Gephyrin - Gphn - Mus musculus
|
| DOC_WW_Pin1_4 | 185 | 190 | Binary | Physicochemical compatibility | Phosphorylation of S188 in the Pin1-binding motif of Gephyrin (Gphn) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 191 | 196 | Binary | Physicochemical compatibility | Phosphorylation of S194 in the Pin1-binding motif of Gephyrin (Gphn) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 197 | 202 | Binary | Physicochemical compatibility | Phosphorylation of S200 in the Pin1-binding motif of Gephyrin (Gphn) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Homeobox protein NANOG - Nanog - Mus musculus
|
| DOC_WW_Pin1_4 | 49 | 54 | Binary | Physicochemical compatibility | Phosphorylation of S52 in the Pin1-binding motif of Homeobox protein NANOG (Nanog) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 62 | 67 | Binary | Physicochemical compatibility | Phosphorylation of S65 in the Pin1-binding motif of Homeobox protein NANOG (Nanog) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Insulin receptor substrate 1 - IRS1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 431 | 436 | Binary | Physicochemical compatibility | Phosphorylation of S434 in the Pin1-binding motif of Insulin receptor substrate 1 (IRS1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Interferon regulatory factor 3 - IRF3 - Homo sapiens
|
| DOC_WW_Pin1_4 | 336 | 341 | Binary | Physicochemical compatibility | Phosphorylation of S339 in the Pin1-binding motif of Interferon regulatory factor 3 (IRF3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
MADS-box protein AGL24 - AGL24 - Arabidopsis thaliana
|
| DOC_WW_Pin1_4 | 199 | 204 | Binary | Physicochemical compatibility | Phosphorylation of T202 in the Pin1-binding motif of MADS-box protein AGL24 (AGL24) induces binding to the Peptidyl-prolyl cis-trans isomerase Pin1 (PIN1) protein. | details |
MADS-box protein SOC1 - SOC1 - Arabidopsis thaliana
|
| DOC_WW_Pin1_4 | 192 | 197 | Binary | Physicochemical compatibility | Phosphorylation of S195 in the Pin1-binding motif of MADS-box protein SOC1 (SOC1) induces binding to the Peptidyl-prolyl cis-trans isomerase Pin1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 46 | 51 | Binary | Physicochemical compatibility | Phosphorylation of S49 in the Pin1-binding motif of MADS-box protein SOC1 (SOC1) induces binding to the Peptidyl-prolyl cis-trans isomerase Pin1 (PIN1) protein. | details |
Mothers against decapentaplegic homolog 3 - SMAD3 - Homo sapiens
|
| DOC_WW_Pin1_4 | 176 | 181 | Binary | Physicochemical compatibility | Phosphorylation of T179 in the Pin1-binding motif of Mothers against decapentaplegic homolog 3 (SMAD3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 201 | 206 | Binary | Physicochemical compatibility | Phosphorylation of S204 in the Pin1-binding motif of Mothers against decapentaplegic homolog 3 (SMAD3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 205 | 210 | Binary | Physicochemical compatibility | Phosphorylation of S208 in the Pin1-binding motif of Mothers against decapentaplegic homolog 3 (SMAD3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 210 | 215 | Binary | Physicochemical compatibility | Phosphorylation of S213 in the Pin1-binding motif of Mothers against decapentaplegic homolog 3 (SMAD3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 176 | 181 | Specificity | Altered binding specificity | CDK8/9 phosphorylates Mothers against decapentaplegic homolog 3 (SMAD3) at T179 and S208. Phosphorylation of T179 creates a binding site for the WW domain of Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1), while phosphorylation of S208 primes SMAD3 for phosphorylation of S204 by Glycogen synthase kinase-3 beta (GSK3B). The pS204-pS208 forms a binding site for the third WW domain of E3 ubiquitin-protein ligase NEDD4-like (NEDD4L), whose second WW domain will displace the WW domain of PIN1 at the pT179-PY box site of SMAD3. This regulation couples SMAD3 activation to SMAD3 destruction in an ordered fashion. See also switch details and switch details. | details |
Myc proto-oncogene protein - MYC - Homo sapiens
|
| DOC_WW_Pin1_4 | 55 | 60 | Binary | Physicochemical compatibility | Phosphorylation of T58 in the Pin1-binding motif of Myc proto-oncogene protein (MYC) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Myocyte-specific enhancer factor 2C - Mef2c - Mus musculus
|
| DOC_WW_Pin1_4 | 107 | 112 | Binary | Physicochemical compatibility | Phosphorylation of S110 in the Pin1-binding motif of Myocyte-specific enhancer factor 2C (Mef2c) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 95 | 100 | Binary | Physicochemical compatibility | Phosphorylation of S98 in the Pin1-binding motif of Myocyte-specific enhancer factor 2C (Mef2c) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Neurogenic locus notch homolog protein 1 - NOTCH1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 2118 | 2123 | Binary | Physicochemical compatibility | Phosphorylation of S2121 in the Pin1-binding motif of Neurogenic locus notch homolog protein 1 (NOTCH1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 2129 | 2134 | Binary | Physicochemical compatibility | Phosphorylation of T2132 in the Pin1-binding motif of Neurogenic locus notch homolog protein 1 (NOTCH1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 2133 | 2138 | Binary | Physicochemical compatibility | Phosphorylation of S2136 in the Pin1-binding motif of Neurogenic locus notch homolog protein 1 (NOTCH1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Neutrophil cytosol factor 1 - NCF1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 342 | 347 | Binary | Physicochemical compatibility | Phosphorylation of S345 in the Pin1-binding motif of Neutrophil cytosol factor 1 (NCF1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Non-POU domain-containing octamer-binding protein - Nono - Mus musculus
|
| DOC_WW_Pin1_4 | 409 | 414 | Binary | Physicochemical compatibility | Phosphorylation of T412 in the Pin1-binding motif of Non-POU domain-containing octamer-binding protein (Nono) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 427 | 432 | Binary | Physicochemical compatibility | Phosphorylation of T430 in the Pin1-binding motif of Non-POU domain-containing octamer-binding protein (Nono) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 449 | 454 | Binary | Physicochemical compatibility | Phosphorylation of T452 in the Pin1-binding motif of Non-POU domain-containing octamer-binding protein (Nono) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Nuclear receptor corepressor 2 - NCOR2 - Homo sapiens
|
| DOC_WW_Pin1_4 | 1238 | 1243 | Binary | Physicochemical compatibility | Phosphorylation of T1241 in the Pin1-binding motif of Nuclear receptor corepressor 2 (NCOR2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 1441 | 1446 | Binary | Physicochemical compatibility | Phosphorylation of T1444 in the Pin1-binding motif of Nuclear receptor corepressor 2 (NCOR2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Nuclear receptor subfamily 4 group A member 1 - NR4A1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 137 | 142 | Binary | Physicochemical compatibility | Phosphorylation of S140 in the Pin1-binding motif of Nuclear receptor subfamily 4 group A member 1 (NR4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 428 | 433 | Binary | Physicochemical compatibility | Phosphorylation of S431 in the Pin1-binding motif of Nuclear receptor subfamily 4 group A member 1 (NR4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 92 | 97 | Binary | Physicochemical compatibility | Phosphorylation of S95 in the Pin1-binding motif of Nuclear receptor subfamily 4 group A member 1 (NR4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
POU domain, class 5, transcription factor 1 - POU5F1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 9 | 14 | Binary | Physicochemical compatibility | Phosphorylation of S12 in the Pin1-binding motif of POU domain, class 5, transcription factor 1 (POU5F1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Protein AATF - AATF - Homo sapiens
|
| DOC_WW_Pin1_4 | 143 | 148 | Binary | Physicochemical compatibility | Phosphorylation of T146 in the Pin1-binding motif of Protein AATF (AATF) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Protein BTG2 - BTG2 - Homo sapiens
|
| DOC_WW_Pin1_4 | 144 | 149 | Binary | Physicochemical compatibility | Phosphorylation of S147 in the Pin1-binding motif of Protein BTG2 (BTG2) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Protein PML - PML - Homo sapiens
|
| DOC_WW_Pin1_4 | 400 | 405 | Binary | Physicochemical compatibility | Phosphorylation of S403 in the Pin1-binding motif of Protein PML (PML) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 502 | 507 | Binary | Physicochemical compatibility | Phosphorylation of S505 in the Pin1-binding motif of Protein PML (PML) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 515 | 520 | Binary | Physicochemical compatibility | Phosphorylation of S518 in the Pin1-binding motif of Protein PML (PML) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 524 | 529 | Binary | Physicochemical compatibility | Phosphorylation of S527 in the Pin1-binding motif of Protein PML (PML) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Protein SPT23 - SPT23 - Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
|
| DOC_WW_Pin1_4 | 651 | 656 | Binary | Physicochemical compatibility | Phosphorylation of S654 in the Pin1-binding motif of Protein SPT23 (SPT23) induces binding to the Peptidyl-prolyl cis-trans isomerase ESS1 (ESS1) protein. | details |
Protein Tax-1 - tax - Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A)
|
| DOC_WW_Pin1_4 | 157 | 162 | Binary | Physicochemical compatibility | Phosphorylation of S160 in the Pin1-binding motif of Protein Tax-1 (tax) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Protein X - X - Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979)
|
| DOC_WW_Pin1_4 | 38 | 43 | Binary | Physicochemical compatibility | Phosphorylation of S41 in the Pin1-binding motif of Protein X (X) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Proto-oncogene c-Fos - Fos - Mus musculus
|
| DOC_WW_Pin1_4 | 229 | 234 | Binary | Physicochemical compatibility | Phosphorylation of T232 in the Pin1-binding motif of Proto-oncogene c-Fos (Fos) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 322 | 327 | Binary | Physicochemical compatibility | Phosphorylation of T325 in the Pin1-binding motif of Proto-oncogene c-Fos (Fos) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 328 | 333 | Binary | Physicochemical compatibility | Phosphorylation of T331 in the Pin1-binding motif of Proto-oncogene c-Fos (Fos) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 371 | 376 | Binary | Physicochemical compatibility | Phosphorylation of S374 in the Pin1-binding motif of Proto-oncogene c-Fos (Fos) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
RAC-alpha serine/threonine-protein kinase - AKT1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 447 | 452 | Binary | Physicochemical compatibility | Phosphorylation of T450 in the Pin1-binding motif of RAC-alpha serine/threonine-protein kinase (AKT1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 89 | 94 | Binary | Physicochemical compatibility | Phosphorylation of T92 in the Pin1-binding motif of RAC-alpha serine/threonine-protein kinase (AKT1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Retinoic acid receptor alpha - RARA - Homo sapiens
|
| DOC_WW_Pin1_4 | 74 | 79 | Binary | Physicochemical compatibility | Phosphorylation of S77 in the Pin1-binding motif of Retinoic acid receptor alpha (RARA) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Serine/threonine-protein kinase Nek6 - NEK6 - Homo sapiens
|
| DOC_WW_Pin1_4 | 212 | 217 | Binary | Physicochemical compatibility | Phosphorylation of S215 in the Pin1-binding motif of Serine/threonine-protein kinase Nek6 (NEK6) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 242 | 247 | Binary | Physicochemical compatibility | Phosphorylation of S245 in the Pin1-binding motif of Serine/threonine-protein kinase Nek6 (NEK6) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Signal transducer and activator of transcription 3 - STAT3 - Homo sapiens
|
| DOC_WW_Pin1_4 | 724 | 729 | Binary | Physicochemical compatibility | Phosphorylation of S727 in the Pin1-binding motif of Signal transducer and activator of transcription 3 (STAT3) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Steroidogenic factor 1 - Nr5a1 - Mus musculus
|
| DOC_WW_Pin1_4 | 200 | 205 | Binary | Physicochemical compatibility | Phosphorylation of S203 in the Pin1-binding motif of Steroidogenic factor 1 (Nr5a1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Sulfotransferase 4A1 - SULT4A1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 5 | 10 | Binary | Physicochemical compatibility | Phosphorylation of T8 in the Pin1-binding motif of Sulfotransferase 4A1 (SULT4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 8 | 13 | Binary | Physicochemical compatibility | Phosphorylation of T11 in the Pin1-binding motif of Sulfotransferase 4A1 (SULT4A1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Synphilin-1 - SNCAIP - Homo sapiens
|
| DOC_WW_Pin1_4 | 208 | 213 | Binary | Physicochemical compatibility | Phosphorylation of S211 in the Pin1-binding motif of Synphilin-1 (SNCAIP) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 212 | 217 | Binary | Physicochemical compatibility | Phosphorylation of S215 in the Pin1-binding motif of Synphilin-1 (SNCAIP) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Telomeric repeat-binding factor 1 - TERF1 - Homo sapiens
|
| DOC_WW_Pin1_4 | 146 | 151 | Binary | Physicochemical compatibility | Phosphorylation of T149 in the Pin1-binding motif of Telomeric repeat-binding factor 1 (TERF1) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Transcription factor AP-1 - JUN - Homo sapiens
|
| DOC_WW_Pin1_4 | 60 | 65 | Binary | Physicochemical compatibility | Phosphorylation of S63 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 70 | 75 | Binary | Physicochemical compatibility | Phosphorylation of S73 in the Pin1-binding motif of Transcription factor AP-1 (JUN) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Transcription factor p65 - RELA - Homo sapiens
|
| DOC_WW_Pin1_4 | 251 | 256 | Binary | Physicochemical compatibility | Phosphorylation of T254 in the Pin1-binding motif of Transcription factor p65 (RELA) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
Transcriptional activator Myb - Myb - Mus musculus
|
| DOC_WW_Pin1_4 | 525 | 530 | Binary | Physicochemical compatibility | Phosphorylation of S528 in the Pin1-binding motif of Transcriptional activator Myb (Myb) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Tumor protein p73 - TP73 - Homo sapiens
|
| DOC_WW_Pin1_4 | 409 | 414 | Binary | Physicochemical compatibility | Phosphorylation of S412 in the Pin1-binding motif of Tumor protein p73 (TP73) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 439 | 444 | Binary | Physicochemical compatibility | Phosphorylation of T442 in the Pin1-binding motif of Tumor protein p73 (TP73) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 479 | 484 | Binary | Physicochemical compatibility | Phosphorylation of T482 in the Pin1-binding motif of Tumor protein p73 (TP73) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) protein. | details |
| DOC_WW_Pin1_4 | 479 | 484 | Binary | Pre‑translational | Alternative splicing removes the WW-binding motif of Tumor protein p73 (TP73), abrogating binding to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1). Isoforms lacking WW-binding motifs have decreased transcriptional activity. | details |
| DOC_WW_Pin1_4 | 439 | 444 | Binary | Pre‑translational | Alternative splicing removes the WW-binding motif of Tumor protein p73 (TP73), abrogating binding to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1). Isoforms lacking WW-binding motifs have decreased transcriptional activity. | details |
| DOC_WW_Pin1_4 | 409 | 414 | Binary | Pre‑translational | Alternative splicing removes the WW-binding motif of Tumor protein p73 (TP73), abrogating binding to Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1). Isoforms lacking WW-binding motifs have decreased transcriptional activity. | details |
Tyrosine-protein kinase BTK - Btk - Mus musculus
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| DOC_WW_Pin1_4 | 112 | 117 | Binary | Physicochemical compatibility | Phosphorylation of S115 in the Pin1-binding motif of Tyrosine-protein kinase BTK (Btk) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
| DOC_WW_Pin1_4 | 18 | 23 | Binary | Physicochemical compatibility | Phosphorylation of S21 in the Pin1-binding motif of Tyrosine-protein kinase BTK (Btk) induces binding to the Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) protein. | details |
Wee1-like protein kinase 1-B - wee1-b - Xenopus laevis
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| DOC_WW_Pin1_4 | 183 | 188 | Binary | Physicochemical compatibility | Phosphorylation of T186 in the Pin1-binding motif of Wee1-like protein kinase 1-B (wee1-b) induces binding to the pin1 protein. | details |
